Circadin
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Product Overview
Circadin is a medication which contains the hormone melatonin. Melatonin naturally occurs in the human body and is involved in regulating our sleep-wake cycle. 2mg tablets
Description
Circadin® 2 mg Prolonged-Release Tablets are a prescription-only melatonin medicine used for the short-term treatment of primary insomnia in adults aged 55 years and over.
Circadin contains melatonin, a hormone naturally produced by the body that helps regulate the sleep–wake cycle. The prolonged-release formulation is designed to release melatonin gradually through the night, helping to improve sleep quality, reduce difficulty falling asleep, and minimise night-time awakenings.
Circadin is indicated only for primary insomnia, meaning sleep disturbance that is not caused by an underlying medical, mental, or environmental condition.
✔ Prolonged-release melatonin formulation
✔ Helps restore natural sleep rhythm
✔ Specifically licensed for adults aged 55+
How to Use
Always take Circadin exactly as prescribed by your doctor or pharmacist.
Recommended Dose
- One tablet (2 mg) once daily
- Take after food, 1–2 hours before bedtime
How to Take
- Swallow the tablet whole with water
- Do not crush, chew, or split the tablet (this affects the prolonged-release action)
Duration of Use
- Treatment may continue for up to 13 weeks
- If sleep problems persist, consult your doctor
Important Use Advice
- Avoid alcohol before, during, or after taking Circadin
- Smoking may reduce effectiveness
- If a dose is missed, do not double dose
Ingredients
Active ingredient
- Melatonin 2 mg per prolonged-release tablet
Other ingredients
- Ammonio methacrylate copolymer type B
- Calcium hydrogen phosphate dihydrate
- Lactose monohydrate
- Colloidal anhydrous silica
- Talc
- Magnesium stearate
⚠ Contains lactose. Not suitable for people with certain sugar intolerances unless advised by a doctor.
Side Effects & Warnings
Do Not Take If
- You are allergic to melatonin or any ingredient
- You are pregnant or breastfeeding
- You are under 55 years of age
Warnings & Precautions
Speak to a doctor or pharmacist before use if you:
- Have liver or kidney problems
- Have an autoimmune condition
- Are taking antidepressants, sleeping tablets, NSAIDs, or medicines that affect melatonin metabolism
⚠ Circadin may cause drowsiness. Use caution with activities requiring alertness.
Possible Side Effects
Uncommon
- Headache or migraine
- Dizziness or drowsiness
- Nausea or indigestion
- Anxiety, irritability, restlessness
- Abdominal pain or dry mouth
Rare but serious
- Chest pain or palpitations
- Fainting
- Visual disturbances
- Mood changes including depression
Frequency not known
- Allergic reactions
- Swelling of the mouth, tongue, or skin
⚠ Stop taking Circadin and seek medical advice immediately if you experience chest pain, fainting, severe mood changes, or signs of an allergic reaction.

