Mefenamic Acid 250mg Capsules (POM) 100 Capsules
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Product Overview
This is a generic product, therefore depending on availability, the brand you receive may not be the same as the one pictured.
Description
Mefenamic Acid 250mg Capsules (100 capsules) is a prescription-only anti-inflammatory painkiller (NSAID) used for short-term relief of pain and inflammation, including period pain (dysmenorrhoea) and other painful conditions where an NSAID is suitable.
Mefenamic acid reduces substances in the body that cause pain and inflammation. It is intended for use as prescribed, using the lowest effective dose for the shortest possible time to reduce the risk of side effects.
Pack size: 100 capsules.
How to Use
Always follow the dispensing label and the patient leaflet supplied with your pack.
How to take
- Take with or immediately after food and swallow with water.
- Take doses evenly spaced, as directed.
- Do not take with other NSAIDs (e.g., ibuprofen, naproxen, aspirin for pain) unless advised.
Typical adult dosing (guide only)
- Doses vary by indication; your prescriber will set the dose and duration. Mefenamic acid is commonly used short-term, particularly for period pain.
Seek medical advice if pain is not improving, if you develop new symptoms (e.g., fever, severe abdominal pain), or if you need it repeatedly each cycle.
Ingredients
Active ingredient: mefenamic acid 250mg per capsule.
Other ingredients (excipients): excipients can vary by manufacturer. The leaflet for a UK mefenamic acid 250mg capsule product states it contains lactose.
For the exact ingredient list for your stock, check the carton/leaflet.
Side Effects & Warnings
Prescription-only medicine (POM).
Do not take and seek advice first if you:
- Have (or have had) a stomach/duodenal ulcer, GI bleeding, or inflammatory bowel disease.
- Are allergic to mefenamic acid/NSAIDs, or have had asthma/wheezing triggered by aspirin/NSAIDs.
- Have significant kidney, liver, heart problems, uncontrolled high blood pressure, or are at higher cardiovascular risk.
- Are pregnant, especially in the last trimester (NSAIDs may be harmful later in pregnancy).
Stop and seek urgent medical help if you get:
- Black/tarry stools, vomiting blood, severe stomach pain (possible GI bleed/ulcer).
- Chest pain, shortness of breath, weakness on one side, slurred speech (possible clot-related event).
- Severe rash, blistering, swelling of face/lips/throat, difficulty breathing (allergic reaction).
Common side effects can include
- Indigestion, stomach pain, nausea/diarrhoea, headache, dizziness.
Interactions (tell your prescriber/pharmacist if you take):
- Anticoagulants (e.g., warfarin/DOACs), antiplatelets, steroids, SSRIs, other NSAIDs, ACE inhibitors/diuretics, lithium or methotrexate.

